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PE anti-mouse TCR Vbeta8.1, 8.2

PE anti-mouse TCR Vbeta8.1, 8.2

Cat no: 118408

Supplier: BioLegend
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The TCR Vbeta 8 family consists of three members, namely Vbeta8.1, 8.2 and 8.3. KJ16-133.18 reacts with Vbeta8.1, 8.2 only, but not Vbeta8.3. Most mouse strains have about 20% Vbeta 8+ T cells in the periphery.However, C57BR, C57L, SJL, SWR (Tcra haplotype) and RIII strains (Tcrc haplotype) do not express Vbeta8 due to a gene deletion at the Vbeta 8 family loci.Other strains expressing endogenous super-antigen, such as Mls-1a have significant reduced number of Vbeta 8.1 cells in the periphery.Exogenous superantigen, such as staphylococcal enterotoxin B, stimulates lymphocytes bearing Vbeta 8 and selectively eliminate those T cells in vivo.
Catalogue number: 118408
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 100 microg
Clone: KJ16-133.18
Gene: 21577
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.2 mg/ml
Antigen: TCR receptor from T cell hybridoma DO-11.10
Isotype: Rat IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: T cell receptor Vb8.1, 8.2 chain, TCR Vb8.1, 8.2
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