PE anti-rat CD25

Cat no: 202105

Supplier: BioLegend

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Description
Additional Information

CD25 is a 55 kD glycoprotein also known as IL-2 receptor alpha chain. It is broadly expressed on activated T and B cells, a subset of thymic and splenic dendritic cells, and intestinal epithelial cells in the rat. IL-2 is a critical cytokine involved in lymphocyte proliferation and clonal expansion. IL-2 signaling requires the high affinity IL-2 receptor composed of IL-2 receptor chains alpha, beta, and gamma. The OX-39 antibody weakly inhibits IL-2 binding to the IL-2 receptor and has been shown to block some IL-2 mediated responses in vitro.

Catalogue number:	202105
Reactivities:	Rat
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	50 microg
Clone:	OX-39
Gene:	16184
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration:	0.2 mg/ml
Antigen:	Rat T cell blasts from mixed lymphocyte reactions
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	IL-2Ra, IL-2 receptor chain a