PE/Cy7 anti-human CD161

Cat no: 339918

Supplier: BioLegend

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Description
Additional Information

CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

Catalogue number:	339918
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	100 tests
Clone:	HP-3G10
Gene:	3820
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen:	Human NK cells
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	NKR-P1A