PE/Cy7 anti-human CD304 (Neuropilin-1)

Cat no: 354507

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

CD304, also known as neuropilin-1, BDCA-4 and VEGF165R, is a 140 kD type I transmembrane protein. Its extracellular region contains 2 CUB, 2 FV/FVIII, and one MAM domain; a soluble isoform is produced by alternative mRNA splicing. CD304 is involved in angiogenesis, neural development, and tumor metastasis. It's expressed by plasmacytoid dendritic cells, thymocytes, neurons, endothelium, and a subset of TFH cells. CD304 is also expressed in several carcinomas, and a high expression of this molecule in prostate cancer correlates with a poor prognosis.

Catalogue number:	354507
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	25 tests
Clone:	12C2
Gene:	8829
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4, and protected from prolonged exposure to light. Do not freeze.
Antigen:	CD304-Fc Fusion protein
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	BDCA-4 (BDCA4), VEGF165R, NRP1