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PE/Cy7 anti-mouse CD49b (pan-NK cells)

PE/Cy7 anti-mouse CD49b (pan-NK cells)

Cat no: 108921

Supplier: BioLegend
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DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin alpha chain also known as alpha2 integrin, VLA-2 alpha chain, and integrin alpha2 chain. CD49b non-covalently associates with CD29 (beta1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Catalogue number: 108921
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 25 microg
Clone: DX5
Gene: 16398
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.2 mg/ml
Antigen: IL-2-propagated NK1.1+ cells from C57BL/6 mice
Isotype: Rat IgM, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: alpha2 integrin, VLA-2 alpha chain, DX5, Integrin alpha2 chain
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