PEDF, Recombinant, Mouse (Pigment Epithelium-derived Factor, Cell Proliferation-inducing Gene 35 Protein, EPC-1, Serpin F1)

Supplier:

United States Biological

Cat no: 045135

PEDF, Recombinant, Mouse (Pigment Epithelium-derived Factor, Cell Proliferation-inducing Gene 35 Protein, EPC-1, Serpin F1)

Pigment epithelium-derived factor (PEDF) is a 47kD secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.\n\nSequence:\nMouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG(R)-tag.\n\nStorage and Stability:\nShort-term Storage: +4 degrees C\nLong-term Storage: -20 degrees C\nStable for at least 1 year after receipt when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

045135

Size

10ug

Form

Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.

Purity

>95% (SDS-PAGE)

Alternative Names

Pigment Epithelium-derived Factor, Cell Proliferation-inducing Gene 35 Protein, EPC-1, Serpin F1

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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