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Products Pemetrexed, Disodium Salt, Heptahydrate (N-[4-[(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium, LY-231514, Alimta)
![Pemetrexed, Disodium Salt, Heptahydrate (N-[4-[(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium, LY-231514, Alimta)](/system/suppliers/default_product_images/000/000/160/main/US-Biological-Life-Sciences.jpg?1386100414)
| Catalogue number: | P3148-07 |
| Size: | 250mg |
| Form: | Supplied as a white to off-white powder. |
| Purity: | ~99% |
| References: | 1. Shih, C., et al. "LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes." Cancer Res. 57:1116-1123 (1997). 2. Shih, C., et al. "LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes." Cancer Res. 57:1116-1123 (1997). 3. Zhao, R., et al. "Marked suppression of the activity of some, but not all, antifolate compounds by augmentation of folate cofactor pools within tumor cells." Biochem. Pharmacol. 61:857-865 (2001). 4. Chattopadhyay, S., et al. "Pemetrexed: biochemical and cellular pharmacology, mechanisms, and clinical applications." Mol. Cancer Ther. 6:404-417 (2007). 5. Hazarika, M., et al. "FDA drug approval summaries: pemetrexed (Alimta(R))." Oncologist 9:482-488 (2004). 6. Cohen, M.H., et al. "FDA drug approval summary: pemetrexed for injection (Alimta(R)) for the treatment of non-small cell lung cancer." Oncologist 10:363-368 (2005). |
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