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Penicillin G, Sodium Salt USP

Cat no: P3200

Penicillin G, Sodium Salt USP

Penicillin G is a broad based antibiotic used in mammalian cell culture. Penicillin G blocks the formation of bacterial cell walls, rendering bacteria unable to multiply and spread. The spectrum of activity of Penicillin G includes many aerobic and anaerobic gram-positive organisms. Aerobes susceptible to Penicillin G include most beta-hemolytic streptococci, beta-lactamase-negative staphylococci, Actinomyces species, some Bacillus anthracis, Corynebacterium species, and Erysipelothrix rhusiopathiae. Most species of anaerobes, including Clostridium species, but excluding beta-lactamase-producing Bacteroides species, are also susceptible to Penicillin G. Penicillin G is easily inactivated by beta-lactamases and has little efficacy against organisms that can produce these enzymes. In addition, Penicillin G is ineffective against those bacteria that are resistant by other mechanisms, such as having a relatively impermeable cell wall. Therefore, Penicillin G has little activity against many staphylococci and most gram-negative bacteria.\n\nAppearance: \nWhite to off white crystalline powder\n\nPurity: \n96-102.0%\n\nPotency: \n1500-1750u/mg\n\nIdentification: \nConforms to USP\n\nSpecific Rotation (C=0.7): +285 to +310 degrees \n\npH:\n 5.5-7.5\n\nLoss on Drying:\n(same/less than)1.0%\n\nAbsorbance:\n264nm: As reported\n280nm: As reported\n325nm: As reported\n\nEndotoxin:\n<0.16U/mg\n\nRelated Substances: (same/less than)1.0%\n\n2-Ethylhexanoic Acid: \n(same/less than)0.5%

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SPECIFICATIONS

Catalog Number

P3200

Size

100g

Alternative Names

Benzylpenicillin sodium; Sodium benzylpenicillinate

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