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PerCP/Cy5.5 anti-mouse CD182 (CXCR2)

PerCP/Cy5.5 anti-mouse CD182 (CXCR2)

Cat no: 129103


Supplier: BioLegend
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CXCR2 is a 7-transmembrane G protein–coupled receptor that is activated by CXC chemokines containing the ELR (Glu-Leu-Arg) motif, including murine CXCL1 (keratinocyte-derived chemokine; KC) CXCL2 (macrophage inflammatory protein 2; MIP-2), CXCL3 (DC inflammatory protein-1; Dcip1) and CXCL5 (LIX). CXCR2 is expressed on neutrophils, keratinocytes, mast cells, eosinophils, macrophages, and lung endothelial cells (1-3). Homing of mast cell progenitors (MCps) to the mouse small intestine involves CXCR2, vascular cell adhesion molecule-1 (VCAM-1), and the interaction of alpha4beta7 integrin with mucosal addressin cellular adhesion molecule-1 (MAdCAM-1) (4). In addition, CXCR2 regulates endothelial VCAM-1 expression, MCp migration and the levels of intraepithelial MC in the lung of aerosolized, antigen-challenged mice (5).
Catalogue number: 129103
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 25 microg
Clone: TG11/CXCR2
Gene: 12765
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application. * PerCP/Cy5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.2 mg/ml
Antigen: C6 rat glioma cell line transfected with mouse CXCR2, Met1-Leu359, Accession# P35343
Isotype: Rat IgG2a
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: CD128b, IL-8RB, Type II IL-8 receptor
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