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Peroxiredoxin 2, 1-198aa, Recombinant, Human (Peroxiredoxin 2, HGNC:9353, MGC4104, NKEFB, PRP, PRXII, TDPX1, TSA, natural killer-enhancing factor B, thiol-specific antioxidant 1, thioredoxin peroxidase 1, thioredoxin-dependent peroxide reductase 1, torin)

Cat no: P3352-10C

Peroxiredoxin 2, 1-198aa, Recombinant, Human (Peroxiredoxin 2, HGNC:9353, MGC4104, NKEFB, PRP, PRXII, TDPX1, TSA, natural killer-enhancing factor B, thiol-specific antioxidant 1, thioredoxin peroxidase 1, thioredoxin-dependent peroxide reductase 1, torin)

Peroxiredoxin 2, also known as PRDX2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. If Peroxiredoxin 2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. \n\nSource:\nRecombinant human Peroxiredoxin 2 protein was expressed in E.coli.\n\nMolecular Weight: 21.8kD (198aa)\n\nBiological Activity:\nSpecific activity is 200-230 pmole/min/ug, and was obtained by measuring the remaining peroxide after incubation of PRDX2 and peroxide for 20min at RT. Specific activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for 1 min.\n\nAA Sequence:\nMASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

P3352-10C

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH8.0, 10% glycerol.

Purity

(same/more than)90% (SDS-PAGE)

References

1. Kim K., et al. (2009), Oncol Rep, 21(6):1391-6. 2. Kim JH., et al. (2008). Clin Cancer Res. 14(8):2326-33.

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Applications

ELISA

Reactivities

Hum

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Applications

IF

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Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

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Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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