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Pf4, Recombinant, Mouse (Platelet Factor 4, PF-4, C-X-C Motif Chemokine 4, Cxcl4, Scyb4)

Cat no: 149683

Pf4, Recombinant, Mouse (Platelet Factor 4, PF-4, C-X-C Motif Chemokine 4, Cxcl4, Scyb4)

PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant murine PF-4 is an 8.2kD protein containing 76aa, including the four highly conserved residues present in CXC chemokines.\n\nSource:\nRecombinant protein corresponding to mouse PF-4, expressed in E.coli.\n\nBiological Activity:\nDetermined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml.\n\nEndotoxin:\n<0.1ng/ug (1EU/ug)\n\nAA Sequence:\nVTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

149683

Size

5ug

Form

Supplied as a lyophilized powder.

Purity

~98% (SDS-PAGE and HPLC)

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