Phosphatase, Alkaline, Placental (Alkaline Phosphatase, Placental Type, Alkaline Phosphatase Regan isozyme, ALP, FLJ61142, PALP, Placental Alkaline Phosphatase 1, PLAP, PLAP-1)

Placental alkaline phosphatase (PLAP) is a membrane-associated sialoglycoprotein enzyme normally present at high concentration in syncytiotrophoblasts within the placenta during the third trimester of gestation. The expression of PLAP was originally thought to be restricted to term placenta but a human PLAP-like variant has been described which shares more than 85% homology with PLAP itself. PLAP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It is also commonly expressed in germ cell tumors and more recently described in seminomas.\n\nConcentration: \n~1mg protein/vial (Coomassie)\n \nActivity: \n~100U/mg protein\n \nUnit Definition:\nOne unit will convert one micromole of p-nitrophenyl phosphate to p-nitrophenol and phosphate per minute at 37 degrees C in the presence of AMP (2-amino-2-methyl-1-propanol) at pH 10.35. \n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Reconstitute with sterile Tris-saline or buffer. Aliquot and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

P4071-16E

Size

100U

Form

Supplied as a lyophilized powder from 25mM Tris, 1mM magnesium, 0.1mM zinc, pH 7.6. No preservative added. Reconstitute with sterile Tris-saline or other buffer.

Purity

Purified