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Phosphotrienin (Fostriecin, Antibiotic CI 920, Antibiotic CL 1565A,  Antibiotic PD 110161, NSC 339638)

Cat no: P4075-25

Phosphotrienin (Fostriecin, Antibiotic CI 920, Antibiotic CL 1565A, Antibiotic PD 110161, NSC 339638)

Fostriecin is the most fully characterized member of a family of phosphate esters of a triene antibiotic. The antitumor potential of fostriecin has attracted considerable interest, focused on its mode of action as a topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein phosphatase PP2A.\n\nPurity: 95% by HPLC, isolated as the sodium salt\n\nSolubility: Soluble in water, optimial stability in aqueous buffered solutions at pH 6.5. Note: hydrolysis of the phosphate ester will result from inappropriate storage.\n\nRelated to: Sultriecin

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SPECIFICATIONS

Catalog Number

P4075-25

Size

100ug

Form

Supplied as a white powder.

Purity

95% by HPLC, isolated as the sodium salt

References

1. Walsh. AH et al., FEBS Lett. 416: 230 (1997) . 2. Guo, X,W et al. EMBO J, 14:976 (1995)

Alternative Names

Fostriecin, Phosphotrienin, Antibiotic CI 920, Antibiotic CL 1565A,Antibiotic PD 110161, NSC 339638

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Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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