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Phrixotoxin-2

Phrixotoxin-2

Cat no: P-700


Supplier: Alomone Labs Ltd.
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Phrixotoxin-2. A Potent Blocker of Kv4 Channels . (k)-theraphotoxin-Ps1b, (k)-TRTX-Ps1b, PaTX2. Phrixotoxin-2 is a natural peptide isolated from the Phrixotrichus auratus Tarantula venom and purified to homogeneity. Phrixotoxin-2 blocks specifically and reversibly Kv4.2 and Kv4.3 channels. These channels are probably the molecular counterparts of the A-type current (Ito1) in the heart. Cloned Kv4.2 and Kv4.3 channels heterologously expressed in COS cell were blocked with IC50 of 34 and 71 nM of Phrixotoxin-2 respectively. Ion Channel Modulators; K+ Channel Blockers.
Catalogue number: P-700
Size: 5 x 5 micro g
Concentration: 30 nM - 1 micro M.
Molecular weight: 3923 da
Purity: >98%
Shipping temp: Room Temperature
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