PIP5KIgamma Peptide

Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking and cytoskeletal organization. The PIPK family is divided into type I, type II and type III. Each type of the PIPK family phosphorylates distinct substrates. They contain an activation loop, which determines their enzymatic specificity and subcellular targeting. The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I alpha, beta and gamma , which are characterized by phosphorylating PI4P on the 5-hydroxyl. PIPK I alpha, designated PIPK I beta in mouse, is expressed in brain tissue. PIPK I beta, designated PIPK I alpha in mouse, is also called STM7. PIPK I gamma has two variants produced by alternative splicing which are expressed in lung, brain and kidneys.

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SPECIFICATIONS

Catalog Number

BS5857P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide PIP5KIgamma . (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

O60331

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5857 PIP5KIgamma pAb.

Alternative Names

Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; PtdIns(4)P-5-kinase 1 gamma; Phosphatidylinositol 4-phosphate 5-kinase type I gamma; PIP5KIgamma; PIP5K1C; KIAA0589; PIP5KI gamma ; PIP5KI-gamma