PIWIL1 Antibody

Cat no: 250823

Supplier: ABBIOTEC

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Description
Additional Information

Piwi-like protein 1 (PIWIL1) plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL1 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming comple, Xenopus/Amphibian,es composed of piRNAs and Piwi proteins and governing the methylation and subsequent repression of transposons. PIWIL1 binds pi RNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism. PIWIL1 is also involved in the formation of chromatoid bodies and is required for some piRNAs stability.

Catalogue number:	250823
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q96J94
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PIWIL1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Piwi-like protein 1; PIWIL1; HIWI