PIWIL2 Antibody

Cat no: 252136

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

Piwi-like protein 2 (PIWIL2) plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL2 plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. PIWIL2 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming comple, Xenopus/Amphibian,es composed of piRNAs and PIWI proteins. PIWIL2 directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements.

Catalogue number:	252136
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q8TC59
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PIWIL2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS, 2% BSA pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Piwi-like protein 2; Cancer/testis antigen 80; CT80; PIWIL2; HILI