PIWIL2 Antibody

Cat no: 252137

Supplier: ABBIOTEC

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Description
Additional Information

Piwi-like protein 2 (PIWIL2) plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL2 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming comple, Xenopus/Amphibian,es composed of piRNAs and Piwi proteins and governing the methylation and subsequent repression of transposons. PIWIL2 binds pi RNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism. PIWIL2 is also involved in the formation of chromatoid bodies and is required for some piRNAs stability.

Catalogue number:	252137
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q8TC59
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within human PIWIL2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by peptide-affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Piwi-like protein 2; Cancer/testis antigen 80; CT80; PIWIL2; HILI