PLGF Antibody

Cat no: 250825

Supplier: ABBIOTEC

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Description
Additional Information

Placenta growth factor (PLGF or PIGF) is a dimeric glycoprotein showing the highest degree of sequence similarity to the vascular endothial growth factor. Alternative splicing of the PLGF primary transcript gives rise to three forms named PIGF-1, 2 and 3, which differ only in the insertion of a highly basic 21-amino acid stretch at the carbo, Xenopus/Amphibian,yl end. PLGF is active in angiogenesis and endothelial cell growth by stimulating their proliferation and migration. PLGF binds to receptor VEGFR-1/FLT1. PLGF-2 binds neuropilin-1 and 2 in a heparin-dependent manner. Whereas the three forms are present in most placental tissues,PorcineIGF-2 is specific to early (8 week) placenta and only PIGF-1 is found in the colon and mammary carcinomas.

Catalogue number:	250825
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P49763
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PLGF.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Placenta growth factor; PIGF; PGFL; PLGF