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PODXL Polyclonal Antibody

Cat no: CAC07547

PODXL Polyclonal Antibody

PODXL Polyclonal Antibody

Prices direct from Biomatik Corporation

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Exclusive Biosave savings/discounts

SPECIFICATIONS

Price

323.00 USD

Catalog Number

CAC07547

Size

100 micro g

Applications

IF, IHC, WB

Hosts

Rabbit

Conjugates

Unconj

Purity

Caprylic Acid Ammonium Sulfate Precipitation Purified

Target

PODXL

Clonality

Polyclonal

Storage Temp

Aliquot and store at -20 degrees C. Minimize freezing and thawing.

Research Area

For research use only. Not for diagnostic procedures.

Shipping Temp

Blue ice

Additional Info

Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.

Alternative Names

GCTM-2 antigen,Gp200,Podocalyxin-like protein 1,PODXL ,PCLP, PCLP1

SUPPLIER INFO

Biomatik Corporation

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

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