Polyclonal Anti-APLP2

Rabbit IgG polyclonal antibody for Amyloid-like protein 2 (APLP2) detection. Tested with WB, IHC-P in Human;Mouse;Rat. \n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1654

Size

100ug/vial

Applications

IHC, WB

Reactivities

Hum, Mouse, Rat

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

APLP2

References

1. Leach, R., Ko, M., Krawetz, S. A. Assignment of amyloid-precursor-like protein 2 gene (APLP2) to 11q24 by fluorescent in situ hybridization. Cytogenet. Cell Genet. 87: 215-216, 1999.\n2. von der Kammer, H., Loffler, C., Hanes, J., Klaudiny, J., Scheit, K. H., Hansmann, I. The gene for the amyloid precursor-like protein APLP2 is assigned to human chromosome 11q23-25. Genomics 10: 308-311, 1994.\n3. Leach R, Ko M, Krawetz SA (1999). \"Assignment of amyloid-precursor-like protein 2 gene (APLP2) to 11q24 by fluorescent in situ hybridization\". Cytogenet. Cell Genet. 87 (3

Swiss Prot

Q06481

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.

Additional Info

A synthetic peptide corresponding to a sequence at the C-terminal of human APLP2, identical to the related rat and mouse sequences.

Scientific Background

APLP2(Amyloid beta (A4) precursor-like protein 2),also known as CDEBP or SPERM MEMBRANE PROTEIN, is a protein that in humans is encoded by the APLP2 gene. The APLP2 gene is mapped on 11q24.3. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. APLP2 along with APLP1 are important modulators of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.