Polyclonal Anti-BAG1

Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 1 (BAG1) detection. Tested with WB, IHC-P, ICC in Human;Rat. \n

Prices direct from BOSTER IMMUNOLEADER

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1392

Size

100ug/vial

Applications

ICC, IHC, WB

Reactivities

Hum, Rat

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

BAG1

References

1. Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC (Mar 1995). \"Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity\". Cell 80 (2): 279

Swiss Prot

Q99933

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

A synthetic peptide corresponding to a sequence at the C-terminal of human BAG1, different from the related mouse sequence by two amino acids.

Scientific Background

BAG family molecular chaperone regulator 1 (BAG1) is a protein that in humans is encoded by the BAG1 gene. Human BAG1 is mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The Bag1 protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.