Polyclonal Anti-BCL3

Rabbit IgG polyclonal antibody for B-cell lymphoma 3 protein (BCL3) detection. Tested with WB, IHC-P in Human;Mouse;Rat. \n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1539

Size

100ug/vial

Applications

IHC, WB

Reactivities

Hum, Mouse, Rat

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

BCL3

References

1. Wulczyn FG, Naumann M, Scheidereit C (Sep 1992). \"Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B\". Nature 358 (6387): 597

Swiss Prot

P20749

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

A synthetic peptide corresponding to a sequence in the middle of human BCL3, different from the related rat and mouse sequence by one amino acid.

Scientific Background

B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene.This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia.The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins.The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.