Polyclonal Anti-Calretinin

Rabbit IgG polyclonal antibody for Calretinin (CALB2) detection. Tested with WB, IHC-P in Human;Mouse;Rat. \n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1015

Size

100ug/vial

Applications

IHC, WB

Reactivities

Hum, Mouse, Rat

Form

Liquid

Format

Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4.

Gene Id

CALB2

References

1. Parmentier M.; \"The human calbindins: cDNA and gene cloning.\";Adv. Exp. Med. Biol. 255:233-240(1989).\n2. Strauss K.I., Kuznicki J., Winsky L., Kawagoe J.I., Hammer M., Jacobowitz D.M.;\"The mouse calretinin gene promoter region: structural and functional components.\";Brain Res. Mol. Brain Res. 49:175-187(1997).\n3. Gabrielides C., McCormack A.L., Hunt D.F., Christakos S.;\"Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry.\";Biochemistry 30:656-662(1991).

Swiss Prot

P22676

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

A synthetic peptide corresponding to a sequence at the N-terminal of human calretinin, identical to the related rat sequence.

Scientific Background

Calbindin is a calcium-binding protein belonging to the troponin C superfamily. Calretinin is expressed in central and peripheral nervous system and in many normal and pathological tissues. The rat and human calretinin exhibit 98% sequence homology and 91% homology to many other species. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum.