

Supplier:
BOSTER IMMUNOLEADERCat no: PA1672
Polyclonal Anti-FGF13
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SPECIFICATIONS
Price
200.00 USD
Catalog Number
PA1672
Size
100ug/vial
Applications
WB
Reactivities
Hum, Mouse, Rat
Form
Lyophilized
Format
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Gene Id
FGF13
References
1. Gecz, J., Baker, E., Donnelly, A., Ming, J. E., McDonald-McGinn, D. M., Spinner, N. B., Zackai, E. H., Sutherland, G. R., Mulley, J. C.Fibroblast growth factor homologous factor 2 (FHF2): gene structure, expression and mapping to the Borjeson-Forssman-Lehmann syndrome region in Xq26 delineated by a duplication breakpoint in a BFLS-like patient.Hum. Genet. 104: 56-63, 1999.\n2. Smallwood, P. M., Munoz-Sanjuan, I., Tong, P., Macke, J. P., Hendry, S. H. C., Gilbert, D. J., Copeland, N. G., Jenkins, N. A., Nathans, J.Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.Proc. Nat. Acad. Sci. 93: 9850-9857, 1996.
Swiss Prot
Q92913
Storage Temp
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.
Additional Info
A synthetic peptide corresponding to a sequence in the middle region of human FGF13(72-87aa KLYSRQGYHLQLQADG), identical to the related rat and mouse sequences.
Scientific Background
FGF13(Fibroblast growth factor 13), also called FHF2 is a protein that in humans is encoded by the FGF13 gene.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF13is a large gene, extending over approximately 200 kb in Xq26.3, and contains at least 7 exons. By cytogenetic, FISH, and database analysis, Gecz et al. (1999) localized the FGF13 gene within a 400-kb duplication interval on chromosome Xq26.3. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
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