Polyclonal Anti-HSPBAP1

Rabbit IgG polyclonal antibody for HSPB1-associated protein 1 (HSPBAP1) detection. Tested with WB in Human. \n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1609

Size

100ug/vial

Applications

WB

Reactivities

Hum

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

HSPBAP1

References

1.Bodmer, D., Schepens, M., Eleveld, M. J., Schoenmakers, E. F. P. M., van Kessel, A. G. Disruption of a novel gene, DIRC3, and expression of DIRC3-HSPBAPI fusion transcripts in a case of familial renal cell cancer and t(2;3)(q35;q21). Genes Chromosomes Cancer 38: 107-116, 2003. \n2.Jiang, M., Ma, Y., Cheng, H., Ni, X., Guo, L., Xie, Y., Mao, Y. Molecular cloning and characterization of a novel human gene (HSPBAP1) from human fetal brain. Cytogenet. Cell Genet. 95: 48-51, 2001.\n

Swiss Prot

Q96EW2

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.

Additional Info

A synthetic peptide corresponding to a sequence at the N-terminal of human HSPBAP1, different from the related rat sequences by one amino acid, and different from the related mouse sequences by two amino acids.

Scientific Background

HSPBAP1(HEAT-SHOCK 27-KD PROTEIN-ASSOCIATED PROTEIN 1)?the other entities represented in this entry is DIRC3 FUSION GENE. HSPBAP1 shares 80% identity with the rat homolog, PASS1. The HSPBAP1 gene is mapped to chromosome 3q21.1. RT-PCR detected expression of HSPABAP1 in all tissues examined except brain. Highest expression was detected in thymus, ovary, and pancreas. The HSPBAP1 gene contains 8 exons. The putative 451-amino acid truncated HSPBAP1 protein retained its JmjC and HSP27 -interacting domains, which are associated with chromatin remodeling and stress response, respectively.