Polyclonal Anti-human IL-10

Rabbit IgG polyclonal antibody for Interleukin-10 (IL10) detection. Tested with WB, IHC-P, ELISA in Human. \n

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SPECIFICATIONS

Price

240.00 USD

Catalog Number

RP1014

Size

100ug/vial

Applications

ELISA, IHC, WB

Reactivities

Hum

Form

Lyophilized

Format

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Gene Id

IL10

References

1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). \"Mapping of the human IL10 gene and further characterization of the 5' flanking sequence\".

Swiss Prot

P22301

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

E. coli-derived human IL-10 recombinant protein (Position: S19-N178).

Scientific Background

Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse Il 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.