Polyclonal Anti-IGFBP6

Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 6 (IGFBP6) detection. Tested with WB in Human;Mouse;Rat. \n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1404

Size

100ug/vial

Applications

WB

Reactivities

Hum, Mouse, Rat

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

IGFBP6

References

1. Kiefer MC, Ioh RS, Bauer DM, Zapf J (May 1991). \"Molecular cloning of a new human insulin-like growth factor binding protein\". Biochem Biophys Res Commun 176 (1): 219

Swiss Prot

P24592

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

A synthetic peptide corresponding to a sequence in the middle region of human IGFBP6, different from the related rat sequence by two amino acids.

Scientific Background

Insulin-like growth factor-binding protein 6 (IGFBP6) is a protein that in humans is encoded by the IGFBP6 gene. The IGFBP6 gene is mapped to chromosome 12. In all, it has contained 216 amino acid protein with a calculated molecular mass of 22,847 Da. Kato et al. (1995) showed that the human keratinocyte cell line HaCat secretes IGFBP6 as an autocrine growth inhibitor. Recombinant IGFBP6 was also shown to inhibit growth of HaCat cells and other keratinocyte cell lines.