Polyclonal Anti-KLIP1

Rabbit IgG polyclonal antibody for Protein YIPF3 (YIPF3) detection. Tested with WB, IHC-P in Human;Mouse;Rat. \n\n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1635

Size

100ug/vial

Applications

IHC, WB

Reactivities

Hum, Mouse, Rat

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

YIPF3

References

1.Prost, S., LeDiscorde, M., Haddad, R., Gluckman, J.-C., Canque, B., Kirszenbaum, M. Characterization of a novel hematopoietic marker expressed from early embryonic hematopoietic stem cells to adult mature lineages. Blood Cells Molec. Dis. 29: 236-248, 2002.

Swiss Prot

Q9GZM5

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.

Additional Info

A synthetic peptide corresponding to a sequence at the N-terminal of human KLIP1, identical to the related rat and mouse sequences.

Scientific Background

KLIP1(KILLER LINEAGE PROTEIN 1), also known as YIPF3. The KL1P1 gene is mapped to chromosome 6p21.1. The KLIP1 gene contains 9 exons and spans about 5 kb. And KLIP1 also contains an N-terminal signal sequence, followed by an extracellular domain, 5 transmembrane regions, and a cytoplasmic C-terminal sequence. KLIP1 expression closely correlated with hematopoietic activity in both intra- and extra-embryonic hematopoietic sites. In day 30/32 human embryo sections, KLIP1 protein expression was restricted to circulating hematopoietic cells at hematopoiesis sites. Western blot analysis of fetal liver extracts and in vitro translated KLIP1 cDNA detected the KLIP1 protein at an apparent molecular mass of 37 kD. Phylogenetic analysis indicated that KLIP1 is highly conserved.