Polyclonal Anti-PNPLA6

Rabbit IgG polyclonal antibody for ANRE Unreviewed (PNPLA6) detection. Tested with WB, IHC-P, IHC-F in Zebrafish. \n

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1226

Size

100ug/vial

Applications

IHC, IHC-Fr, WB

Form

Liquid

Format

Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4.

Gene Id

PNPLA6

References

1. Winrow, C. J.; Hemming, M. L.; Allen, D. M.; Quistad, G. B.; Casida, J. E.; Barlow, C. : Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity. Nature Genet. 33: 477-486, 2003.

Swiss Prot

F1R844

Storage Temp

\"At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.\nAvoid repeated freezing and thawing. \n\"\n

Additional Info

A synthetic peptide corresponding to a sequence at the C-terminal of fish PNPLA6

Scientific Background

Patatin-like phospholipase domain containing 6 (PNPLA6), also known as Neuropathy target esterase (NTE), is a human gene. Neuropathy target esterase (NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging.