Polyoxyethylenesorbitan Monolaurate (Tween 20)

Tween-20 is a polysorbate surfactant whose stability and relative non-toxicity allow it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications. It is a polyoxyethylene derivative of sorbitan monolaurate, and is distinguished from the other members in the Tween range by the length of the polyoxyethylene chain. The commercial product contains a range of chemical species.\n\nAppearance:\nYellow to amber viscous liquid.\n\nHydroxyl Number: \n96-108\n\nWater: \n(same/less than)3%\n\nResidue of Ignition:\n(same/less than)0.25%\n\nArsenic:\n(same/less than)0.0003%\n\nHeavy Metals: \n(same/less than)0.001%\n\nRNase, DNase:\nNone Detected\n\nBiological applications:\nTween 20 has a broad range of applications. For example, it is used: \nto stabilize purified protein derivative (PPD) solution, used in skin testing for tuberculosis exposure, as a blocking agent in immunologic assays, such as Western blots and ELISA and as a solubilizing agent of membrane proteins for lysing mammalian cells, at a concentration of 0.05 to 0.5%.

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SPECIFICATIONS

Catalog Number

P4379

Size

1L

References

1. Ayorinde FO, Gelain SV, Johnson JH Jr, Wan LW. (2000). \"Analysis of some commercial polysorbate formulations using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry\". Rapid Communications in Mass Spectrometry 14 (22): 2116-2124. PMID 11114018. Retrieved on 7 August 2006.. 2. Joint FAO/WHO Expert Committee on Food Additives (1974). Toxicological evaluation of some food additives including anticaking agents, antimicrobials, antioxidants, emulsifiers and thickening agents. WHO Food Additives Series No. 5. World Health Organization. Retrieved on 7 August 2006