Human AB plasma is collected from healthy male donors at FDA-licensed facilities located entirely within the U.S. These individual units are converted to serum and then pooled, filtered, bottled and cell culture tested for mycoplasma, endotoxin, and sterility. Each individual unit is tested and found negative for all required viral markers via FDA-Approved methods (HBsAg, HIV-1, HIV-2, HCV, HIV-1Ag or HIV-1 NAT, ALT and syphilis).