PP-1 Antibody

The protein phosphatase 1 (PP1) is essential for cell division and participates in the regulation of glycogen metabolism,Mouse,uscle contractility and protein synthesis. PP-1 is involved in the regulation of ionic conductances and long-term synaptic plasticity. PP-1 plays an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. PP-1 holoenzyme is a trimeric comple, Xenopus/Amphibian, composed of a regulatory subunit, a variable subunit and a catalytic subunit. The PP1 catalytic subunit can be PP1-alpha (PPP1CA),PorcineP1-beta (PPP1CB) or PP1-gamma (PPP1CC), which is folded into its native form by inhibitor 2 and glycogen synthethase kinase 3, and then comple, Xenopus/Amphibian,ed to one or several targeting or regulatory subunits. This antibody recognizes PP1-alpha,PorcineP1-beta and PP1-gamma.

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SPECIFICATIONS

Catalog Number

250829

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PP-1.

Isotype

Mouse Ig

Accession

P62136,Porcine62140,Porcine36873

Additional Info

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; PP-1A; PPP1CA; PPP1A; Serine/threonine-protein phosphatase PP1-beta catalytic subunit; PP-1B; PPP1CB; Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; PP-1G; Protein phosphatase 1C catalytic subunit; PPP1CC