PP6C Antibody

Cat no: 252096

Supplier: ABBIOTEC

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Description
Additional Information

Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C A) is the catalytic subunit of protein phospatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. The N-terminal domain of PP6C A restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. PP6C A downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. PP6C A is ubiquitously e, Xenopus/Amphibian,pressed in all tissues tested with highest e, Xenopus/Amphibian,pression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen.

Catalogue number:	252096
Reactivities:	Human, Mouse, Rabbit
Applications:	Western Blot
Size:	0.1 mg
Accession:	O00743
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PPP6C.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Serine/threonine-protein phosphatase 6 catalytic subunit; PP6C; PPP6C; PPP6