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PPA1 pAb

PPA1 pAb

Cat no: BS6699


Supplier: Bioworld Technology, Inc.
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PPA1 (Pyrophosphate phospho-hydrolase 1), also known as IOPPP (inorganic pyrophosphatase), PP1, PP or PPase, belongs to the PPase family of inorganic pyrophosphatases. Inorganic pyrophosphatases catalyze the intracellular conversion of pyrophosphate to inorganic phosphate, a key reaction for phosphate metabolism in cells. PPA1 is a ubiquitously expressed protein that localizes to the cytoplasm and is required for cell growth. It exists as a homodimer exhibiting magnesium dependent activity. The binding of two magnesium ions is required to stimulate PPA1 activity; however, both subunits in the homodimer are capable of binding four magnesium ions. The additional ions are useful in forming complexes with substrates and products. In addition, the activity of PPA1 can be inhibited by calcium.
Catalogue number: BS6699
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q15181
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human PPA1.
Species: PPA1 pAb detects endogenous levels of PPA1 protein.
Molecular weight: ~ 32 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Inorganic pyrophosphatase; IOPPP; IPYR; PPA1; PPase; Pyp; Pyrophosphate phospho hydrolase; Pyrophosphate phospho-hydrolase;
Additional info: For research use only, not for use in diagnostic procedure.

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