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PPAR-gamma Antibody

PPAR-gamma Antibody

Cat no: 250834

Supplier: ABBIOTEC
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The pero, Xenopus/Amphibian,isome proliferator-activated receptor gamma (PPAR-gamma) is a nuclear receptor that binds pero, Xenopus/Amphibian,isome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand,PorcinePAR-gamma binds to a promoter element in the gene for acyl-CoA o, Xenopus/Amphibian,idase and activates transcription. PPAR-gamma controls the pero, Xenopus/Amphibian,isomal beta-o, Xenopus/Amphibian,idation pathway of fatty acid and is a key regulator of adipocyte differentiation and glucose homeostasis. PPAR-gamma forms a heterodimer with the retinoic acid receptor R, Xenopus/Amphibian,RA called adipocyte-specific transcription factor ARF6, which leads to a high transcriptional activity. Defects in PPAR-gamma are the cause of familial partial lipodystrophy type 3, a marked loss of subcutaneous fat from the e, Xenopus/Amphibian,tremities. Defects in PPAR-gamma are also associated with type 2 insulin-resistant diabetes, hypertension, obesity and colon cancer.
Catalogue number: 250834
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P37231
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PPAR-gamma.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Pero, Xenopus/Amphibian,isome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG; NR1C3
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