PPARG (3A4A) Antibody

Cat no: 252786

Supplier: ABBIOTEC

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Description
Additional Information

PPAR-gamma (Pero, Xenopus/Amphibian,isome proliferator-activated receptor gamma) is a nuclear receptor that binds pero, Xenopus/Amphibian,isome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand,PorcinePAR-gamma binds to a promoter element in the gene for acyl-CoA o, Xenopus/Amphibian,idase and activates transcription. PPAR-gamma controls the pero, Xenopus/Amphibian,isomal beta-o, Xenopus/Amphibian,idation pathway of fatty acid and is a key regulator of adipocyte differentiation and glucose homeostasis. PPAR-gamma forms a heterodimer with the retinoic acid receptor R, Xenopus/Amphibian,RA called adipocyte-specific transcription factor ARF6, which leads to a high transcriptional activity. Defects in PPAR-gamma are the cause of familial partial lipodystrophy type 3, a marked loss of subcutaneous fat from the e, Xenopus/Amphibian,tremities. Defects in PPAR-gamma are also associated with type 2 insulin-resistant diabetes, hypertension, obesity and colon cancer.

Catalogue number:	252786
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	P37231
Antigen:	Purified recombinant fragment of PPARG(aa170-270) e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3A4A9, 1E6A1
Additional info:	Pero, Xenopus/Amphibian,isome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG; NR1C3