PPP1R11, Recombinant, Human, aa1-126, His-Tag (Protein Phosphatase 1 Regulatory Subunit 11, HCG-V, HCGV, IPP3, TCTE5, TCTEX5)

Supplier:

United States Biological

Cat no: 137168

PPP1R11, Recombinant, Human, aa1-126, His-Tag (Protein Phosphatase 1 Regulatory Subunit 11, HCG-V, HCGV, IPP3, TCTE5, TCTEX5)

Protein phosphatase 1 regulatory subunit 11, also known as PPP1R11, is a 126 amino acid protein that is expressed in a variety of both adult and fetal tissues. PPP1R11 functions as an inhibitor of PP1 (protein phosphatase 1), specifically exhibiting a sensitivity toward the metal-independent and metal-dependent forms of PP1. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. \n\nSource: \nRecombinant protein corresponding to human PPP1R11, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~16.3kD (149aa) (MALDI-TOF)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMAEAGAG LSETVTETTV TVTTEPENRS LTIKLRKRKP EKKVEWTSDT VDNEHMGRRS SKCCCIYEKP RAFGESSTES DEEEEEGCGH THCVRGHRKG RRRATLGPTP TTPPQPPDPS QPPPGPMQH\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137168

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.2M NaCl, 20% glycerol, 1mM DTT.

Purity

~90% (SDS-PAGE)

References

1. Giffon T., et al. (1996) Immunogenrtics. 44:331-339. 2. Zhang J., et al. (1998) Biochemistry. 37:16728-16734.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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