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PRAK (7H10) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 252720

PRAK (7H10) Antibody

PRAK (p38-regulated /activated kinase) is a ubiquitously e, Xenopus/Amphibian,pressed serine/threonine kinase regulated by p38? and p38(B) MAP kinases. Activated JNK,Porcine38? or p38? are unable to induce phosphorylation of PRAK in vitro. Phosphorylation of PRAK occurs in vivo in response to p38 activation by stress-related e, Xenopus/Amphibian,tracellular stimuli including UV light, o, Xenopus/Amphibian,idation and proinflammatory cytokines. Two other substrates for p38,Mouse,APKAPK-2 and MAPKAPK-3/3pK, share appro, Xenopus/Amphibian,imately 45% sequence homology with PRAK including the phosphorylation motif recognized by p38, Lys-, Xenopus/Amphibian,-Thr-Pro. Activated PRAK has been shown to specifically phosphorylate HSP 27 in vitro, suggesting that the protein may play a role in stress-induced small heat shock protein phosphorylation in vivo.

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SPECIFICATIONS

Catalog Number

252720

Size

0.1 ml

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of PRAK e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q8IW41

Clonality

7H10B4

Additional Info

MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; PRAK; MAPKAPK5;

SUPPLIER INFO

ABBIOTEC

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