PRDX4 pAb

PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis. The human PRX IV gene is abundantly expressed in many tissues. PRX IV exists as a precursor protein, which is only detected in testis, and a processed secreted form.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS6787

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human PRDX4.

Species

PRDX4 pAb detects endogenous levels of PRDX4 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

Q13162

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 31 kDa

Alternative Names

Antioxidant enzyme 372; \nAntioxidant enzyme AOE372; \nAOE37 2; \nAOE37-2; \nAOE372; \nEC 1.11.1.15; \nPeroxiredoxin IV; \nPeroxiredoxin-4; \nPeroxiredoxin4; \nPRDX 4; \nPRDX4; \nPRDX4; \nPRX 4; \nPrx IV; \nPrx-IV; \nPRX4; \nPrxIV; \nThioredoxin dependent peroxide reductase A0372; \nThioredoxin Peroxidase (Antioxidant Enzyme); \nThioredoxin peroxidase; \nThioredoxin peroxidase AO372; \nThioredoxin-dependent peroxide reductase A0372; \nTRANK; \n\n