Prealbumin, aa21-147, Recombinant, Human (TTR, Transthyretin, TBPA, ATTR, PALB)

Supplier:

United States Biological

Cat no: P6000-02

Prealbumin, aa21-147, Recombinant, Human (TTR, Transthyretin, TBPA, ATTR, PALB)

Prealbumin, also known Transthyretin, is a tetrameric human plasma protein that is synthesized mainly in the liver. This protein transports the thyroid hormone thyroxine (T4) and retinol (Vitamin A). It is the best indicator of protein-energy malnutrition because it has a circulating half life of 2 days and responds rapidly to changes in nutritional status. Also point-mutations of its gene are known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC). \n\nRecombinant human Prealbumin was expressed in E.coli and purified by using conventional chromatography.\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nEndotoxin: (same/less than)1EU/1ug (LAL).\n\nAmino Acid Sequence:\nMGPTGTGESK CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT TEEEFVEGIY KVEIDTKSYW KALGISPFHE HAEVVFTAND SGPRRYTIAA LLSPYSYSTT AVVTNPKE\n\nMolecular Weight: 13.8kD (128aa)\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

P6000-02

Size

100ug

Applications

WB

Form

Supplied as a liquid in PBS, pH7.4, 10% glycerol.

Purity

~95% by SDS-PAGE.

References

Ando Y., et al. (2009) Rinsho Byori. 57(3):228-35. Shenkin A., et al. (2006) Clin Chem. 52(12):2177-9.

Alternative Names

TTR, Transthyretin, TBPA, ATTR, PALB

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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