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PRG4 (Proteoglycan 4, Lubricin, Megakaryocyte-stimulating Factor, Superficial Zone Proteoglycan, MSF, SZP)

Cat no: P8930-03A


Supplier: United States Biological
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Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P8930-03A
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Jay GD, Torres JR, Warman ML, Laderer MC, Breuer KS. The role of lubricin in the mechanical behavior of synovial fluid. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6194-9. Epub 2007 Apr 2.
Additional info: Recognizes PRG4. Species sequence homology: Human.

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