PRL pAb

Cat no: BS6708

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The anterior pituitary secretes a variety of hormones that are involved in cell growth, differentiation and development. Prolactin, a 226 amino acid protein, plays a role in multiple processes, including cell growth, reproduction and immune function. Full-length Prolactin, as well as an alternative splice product lacking the third exon, are secreted by endothelial cells involved in angiogenesis. In addition to its role in mammary developmant and lactation, Prolactin is known to play a role in the development of mammary cancer, acting as both a mitogen and a differentiating agent. Prolactin has also been shown to enhance the proliferation of B cell hybridomas, leading to an overall increase in antibody production. In addition, Prolactin has been demonstrated to reverse the antiproliferative effects of the immunosuppressive cytokine TGF-beta. Prolactin is also associated with a variety of autoimmune diseases, including arthritis and type 1 diabetes.

Catalogue number:	BS6708
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P01236
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human PRL.
Species:	PRL pAb detects endogenous levels of PRL protein.
Molecular weight:	~ 26 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Lactogenic hormone; Luteotropic hormone; Mammotropin; PRL; Prolactin; Prolactin precursor;
Additional info:	For research use only, not for use in diagnostic procedure.

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PRL pAb

Cat no: BS6708

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