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Profilin-2 Peptide

Profilin-2 Peptide

Cat no: BS60364P

Supplier: Bioworld Technology, Inc.
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Profilins (Profilin-1, Profilin-2 and Profilin-3) act as nucleotide exchange factors that use ATP to charge Actin, a process that regulates Actin polymerization by subsequently sequestering the Actin monomer. Profilin-2, also known as PFN2 or PFL, is a 140 amino acid protein that is ubiquitously expressed with highest expression in kidney, brain and skeletal muscle. Like other members of the Profilin family, Profilin-2 functions as an Actin monomer-binding protein that influences the structure of the cytoskeleton by regulating Actin polymerization in response to extracellular signals. High levels of Profilin-2 inhibit Actin polymerization, while lower levels enhance Actin polymerization, suggesting that the expression of Profilin-2 is regulated by the need for polymerization within the cell. Two isoforms of Profilin-2 exist due to alternative splicing events.
Catalogue number: BS60364P
Applications: Block/Neutralize/Inhibit
Swiss prot: P35080
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Profilin-2. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Profilin2; Profilin 2; Profilin II; PFN2
Additional info: This peptide can be used with studies using BS60364 Profilin-2 pAb.

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