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Prostate Specific Antigen, active, Human, ~99% (PSA, Kallikrein-3, Kallikrein III, Seminin, Semenogelase, g-Seminoprotein, P-30 antigen, KLK3)

Prostate Specific Antigen, active, Human, ~99% (PSA, Kallikrein-3, Kallikrein III, Seminin, Semenogelase, g-Seminoprotein, P-30 antigen, KLK3)

Cat no: P9054-66

Supplier: United States Biological
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Prostate Specific Antigen (PSA, Kallikrein-3, Kallikrein III, Seminin, Semenogelase, g-Seminoprotein, P-30 antigen) is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. Anti-PSA is useful in the positive identification of metastatic deposits of prostatic origin. Applications: Suitable for antigenic applications in immunological protocols. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
Catalogue number: P9054-66
Applications: ELISA
Size: 250ug
Form: Supplied as a sterile-filtered liquid in PBS, pH 7.6, 0.05% sodium azide.
Purity: ~99% (Iodination grade); Enzymatically active PSA antigen. PSA content determined by Abbott ELISA, total protein by Lowry and Optical density; SDS-PAGE shows single band.

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