Prostatic Acid Phosphatase (Prostatic Acid Phosphotase, PAP, Acid Phosphatase Prostate, ACPP, ACP3, ACP-3)

Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of acid phosphatase are found in metastasized prostate cancer. Diseases of the bone, such as Paget's disease or hyperparathyroidism, diseases of blood cells, such as sickle-cell disease or multiple myeloma or lysosomal storage diseases, such as Gaucher's disease, will show moderately increased levels. Certain medications can cause temporary increases or decreases in acid phosphatase levels. Manipulation of the prostate gland through massage, biopsy or rectal exam before a test may increase the level.\n\nApplications: \nSuitable for use in ELISA or antigenic applications in immunological protocols. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

P9054-68

Size

1ml

Applications

ELISA

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid, 0.1% sodium azide.

P Type

Pab

Purity

Serum

Isotype

IgG

References

1. Taira A, Merrick G, Wallner K, Dattoli M (July 2007). \"Reviving the acid phosphatase test for prostate cancer\". Oncology (Williston Park, N.Y.) 21 (8): 1003-10. PMID 17715699.\n2. Genega EM, Hutchinson B, Reuter VE, Gaudin PB (November 2000). \"Immunophenotype of high-grade prostatic adenocarcinoma and urothelial carcinoma\". Mod. Pathol. 13 (11): 1186-91. doi:10.1038/modpathol.3880220. PMID 11106075. 3. M

Additional Info

Recognizes human PAP: 100%.