Proteinase 3 (3B4) Antibody

Cat no: 252909

Supplier: ABBIOTEC

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Description
Additional Information

PRTN3 (Proteinase 3) is a serine protease enzyme e, Xenopus/Amphibian,pressed mainly in neutrophil granulocytes. Its e, Xenopus/Amphibian,act role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.

Catalogue number:	252909
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	P24158
Antigen:	Purified recombinant fragment of human PRTN3 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml IgG (1 mg/ml) in PBS pH7.4, 50% glycerol with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2b
Clonality:	3B4
Additional info:	Myeloblastin; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen; MBN; PRTN3