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PSEN1 Polyclonal Antibody

Cat no: CAC07620

PSEN1 Polyclonal Antibody

PSEN1 Polyclonal Antibody

Prices direct from Biomatik Corporation

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Exclusive Biosave savings/discounts

SPECIFICATIONS

Price

323.00 USD

Catalog Number

CAC07620

Size

100 micro g

Applications

IHC, WB

Hosts

Rabbit

Conjugates

Unconj

Purity

Protein G purified, >95%

Target

PSEN1

Clonality

Polyclonal

Storage Temp

Aliquot and store at -20 degrees C. Minimize freezing and thawing.

Research Area

For research use only. Not for diagnostic procedures.

Shipping Temp

Blue ice

Additional Info

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis.

Alternative Names

Presenilin-1,Protein S182,Presenilin-1 NTF subunit,Presenilin-1 CTF subunit,Presenilin-1 C,PSEN1,AD3,PS1,PSNL1

SUPPLIER INFO

Biomatik Corporation

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

Applications

ELISA

Reactivities

Hum

More info

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