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Pseurotin A

Cat no: P9176-45

Pseurotin A

Pseurotin A is a fungal metabolite with an unusual hetero-spirocyclic ring system. It has been shown to have potent neuritogenic activity in PC12 phaechromocytoma cells, a useful model for adrenergic neuronal differentiation. Pseurotin A induced multipolar and branching neurites comparable to beta-NGF, an endogenous neurotrophic factor. Pseurotin A is also reported to exhibit chitinase inhibition and displays synergistic activity with azole antifungal agents.\n\nPurity: >99% by HPLC\n\nSolubility: Soluble in ethanol, methanol, DMF or DMSO.

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SPECIFICATIONS

Catalog Number

P9176-45

Size

1mg

Purity

>99% by HPLC

References

1. Novel neuritogenic activities of pseurotin A and penicillic acid. Komagata D. et al. J. Antibiot. 1996, 49, \n958. \n2. Synerazol, a new antifungal antibiotic. Ando O. et al. J. Antibiot. 1991, 44, 382. \n3. Pseurotin, a new metabolite of Pseudeurotium ovalis Stolk having an unusual hetero-spirocyclic system. \nBloch P. et al. Helv. Chim. Acta 1976, 59, 133.

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