The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Positive modulator of Tat-mediated transactivation. Interacts with the HIV-1 Tat transactivator. Located in both cytoplasmic and nuclear.
Source:
Recombinant protein corresponding to PSMC2, fused to T7 tag at N-terminal expressed in E.coli.
Molecular Weight:
~49.8kD
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Aliquot to avoid repeated freezing and thawing and store at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.